Cae Pwll y Bo Nature Reserve, a small area of rough grassland, has a secluded and remote location in the Cambrian Mountains of central Wales, 4 miles north of Llanwrtyd Wells along the steep-sided valley of the River Irfon. The slopes along this section of the valley are wooded, covered by an extensive conifer plantation established in the mid 20th century, apart from the grassland, a narrow strip of damp pasture adjacent to the river, only about 400 feet long and 60 feet wide; a remnant of a much larger field that once stretched uphill several hundred feet to the road to Pwll-y-Bo farm.
Pwll-y-Bo is Welsh for hobgoblin pool, presumably named after a deep section along the river, though this is not shown on any map. The farm building still survives, in a clearing in the conifer plantation, and is reached by a gravel track off the (unnamed) road through the Irfon valley, nearly opposite a Forestry Commission picnic area which serves as a parking place for visitors to the nature reserve - beside a small grassy area overlooking the river, here flowing forcefully past dark grey boulders. This location is one mile south of the village of Abergwesyn, while the nature reserve is 500 feet away, and as the meadow is so small, around half an acre in area, it can be explored in just a few minutes. The globeflowers are concentrated in the centre of the grassland, a short distance west of the entrance gate.